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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

K. Kontodimas

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Open access Aug 2026

LATS1/2 inactivation drives a distinct venous endothelial cell response that contributes to fibrotic remodeling of the lung

Endothelial dysfunction is recognized to contribute to chronic tissue remodeling in the lung, yet endothelial-derived mechanisms driving these processes remain largely undefined. Here, we show that endothelial inactivation of the LATS1 and LATS2 kinases, key suppressors of the transcriptional regulators YAP and TAZ, el...

K. Kontodimas, A. Raslan, Benjamin Spira et al. · 0 citations
Review Aug 2026

Hippo-YAP/TAZ Signaling in the Respiratory System.

The spatiotemporal control of core pathway components in murine and human lungs is reviewed, highlighting how YAP and TAZ integrate mechanical and molecular cues to govern epithelial patterning, mesenchymal function, vascular integrity, and stem cell behavior.

K. Kontodimas, X. Varelas · 0 citations
Open access Aug 2026

ACKR1-expressing venous endothelial cells establish a pro-fibrotic niche in pulmonary fibrosis

In vitro co-culture assays using ACKR1+ VECs isolated from IPF lungs demonstrate that these cells drive myeloid recruitment and fibroblast activation through ACKR1 dependent mechanisms and show that pharmacologic inhibition of ACKR1 attenuates experimental lung fibrosis.

K. Kontodimas, A. Raslan, Benjamin Spira et al. · 0 citations

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