Aug 2026
Tumor-tropic E. coli engineered as living T and NK cell engagers
Shao-Bo Yang, Anna Clara Bader, S. Sendker et al.
· bioRxiv · 0 citations
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Sep 2026
Cancers modulate processing and presentation of p53 neoantigens to evade T cell detection.
TP53 mutations occur early in malignant transformation as truncal events in tumor evolution and are therefore generally present in all descendant tumor cells, creating an immunological vulnerability. Here, we examined the immunogenicity and antigenicity of p53 neoantigens emerging from these truncal mutations. Comprehe...
Koji Haratani, Bruce R. Reinhold, J. Duke-Cohan et al.
· Immunity · 0 citations
Open access
Sep 2026
Heterogeneous and conserved radiation responses reveal FOXM1-dependent regulation of microcephaly genes in glioblastoma
Glioblastoma (GBM) is characterized by marked heterogeneity, glioma stem-like cells (GSCs), and resistance to therapy. Because GSCs share features with neural progenitor cells (NPCs), we investigated whether neurodevelopmental programs contribute to their response to irradiation. Transcriptional profiling of four patie...
L. Van Eupen, E. Etlioglu, K. Tabury et al.
· bioRxiv · 0 citations