Age-Stratified Analysis of Blood–Brain Barrier Proteins Identifies Lower Occludin Abundance in the 3xTg-AD Model
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder in which blood–brain barrier (BBB) dysfunction may arise early. We performed an age-stratified, cross-sectional analysis of pericyte- and endothelial-associated markers and junctional proteins (claudin-1, -3, -5, occludin, and VE-cadherin) in cerebral...