K. K. Mahato

Multimodal characterization of temperature-induced structural remodeling and aggregation of regenerated silk fibroin

Regenerated silk fibroin (RSF) is a protein biomaterial whose molecular conformation, aggregation behavior, and functional properties are strongly influenced by processing conditions. The current study investigated the structural response of RSF to thermal treatment following incubation at 50–100 °C for 3 h. Intrinsic...

The Nutrition-Sleep-Circadian Axis in Age-Related Neurodegeneration: Cellular Mechanisms, Metabolic Dysfunction, and Neuroprotective Interventions.

Advanced age is accompanied by progressive metabolic, nutritional, mitochondrial, and neuroimmune dysregulation, which may increase susceptibility to neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD), highlighting the need to identify modifiable mechanisms that influence disease...

Label-Free Evaluation of Advanced Glycation End Products by a Comprehensive Biophysical Analysis

An autofluorescence-based methodology (LED-induced autofluorescence) for detecting and tracking the formation of AGEs on proteins using a low-power fiber-coupled near-UV LED and a blue LED as excitation sources covering the heterogeneous excitation maxima of multiple AGEs that form on proteins.

From bean to bar 5.0: Artificial intelligence, sensing technologies and robotics across the cocoa–chocolate value chain