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K. Moreland

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Open access Sep 2026

Molecular determinants of ligand recognition and efficacy in the TRPM3 voltage sensor-like domain

Transient receptor potential melastatin 3 (TRPM3) is a calcium-permeable ion channel implicated in chronic pain and developmental and epileptic encephalopathies. The voltage sensor-like domain (VSLD) is a major site of pharmacological modulation, but the molecular determinants of ligand recognition and efficacy remain...

Vikram Dalal, V. Rangari, Samuel Eriksson Lidbrink et al. · 0 citations

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