Author

K. Moremen

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Review Open access Aug 2026

Role of EXT Family Enzymes in Heparan Sulfate Biosynthesis.

Heparan sulfate (HS) proteoglycans are essential regulators of cell signaling, development, and extracellular matrix organization. Central to the HS biosynthesis pathway is the exostosin family of enzymes that control commitment to HS assembly and catalyze formation of the polymer backbone in the Golgi apparatus. Recen...

Digantkumar G Chapla, K. Moremen · Journal of Histochemistry an... · 0 citations

Open access Aug 2026

Pectin O-3 deacetylation by Arabidopsis thaliana pectin acetylesterase 11 is important for sequential homogalacturonan degradation.

Pectin is a complex plant cell wall polysaccharide whose galacturonic acid residues can be acetylated at O-2 and/or O-3 positions. The degree of acetylation is regulated by pectin acetyl esterase (PAE, EC 3.1.1.6). However, the structure and function of plant PAEs is unclear, impairing our understanding of the role of...

Juliette Chislard, Liang Zhang, Romain Roulard et al. · International Journal of Bio... · 0 citations