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Open access Jul 2026

Neuroprotective Effects of Empagliflozin Against Methamphetamine-Induced Withdrawal Syndrome in Mice: Involvement of Bdnf, Tlr4, and JNK Signaling Pathways and Oxidative Stress Biomarkers

Empagliflozin confers robust behavioral, antioxidant, anti-inflammatory, and neuroprotective effects during methamphetamine withdrawal, and this animal study support empagliflozin as a potential treatment for neuropsychiatric dysfunction associated with METH withdrawal.

H. Ghavimi, M. Ebrahimi, Maede Hasanzadeh et al. · 0 citations

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