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K. Nyrop

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Open access Sep 2026

p16INK4a and DNA methylation clocks in women treated with chemotherapy for early breast cancer.

Candidate biomarkers of biologic aging include p16INK4a (p16) expression in peripheral blood T cells, a marker of cellular senescence, and whole-blood DNA methylation (DNAm) clocks, markers of epigenetic aging. Both have been associated with age-accelerating conditions, including cancer and chemotherapy, but their rela...

H. Muss, Can-Lan Sun, Yuan C. Ding et al. · 0 citations
Open access Aug 2026

Tumor Characteristics and Event Free Survival in Older and Younger Women with Early Breast Cancer

In a sample of women with Stage I-III breast cancer who received chemotherapy with curative intent, triple negative subtype, smoking history, tumor size, and surgery type were significantly associated with shorter five-year event free survival.

Samantha Kodikara, Alexis C. Wardell, A. Deal et al. · 0 citations

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