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K. Obama

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Open access Aug 2026

VA02.6. Systematic En-Bloc Upper Mediastinal Dissection in Robot-Assisted Minimally Invasive Esophagectomy

Esophageal Cancer: Surgical Treatment of Esophageal Cancer We advocated for the mesenteric excision of the upper esophagus (Surg Endosc., 2019). The mesoesophagus, which is surrounded by fibrous connective tissue (visceral sheath), is an anatomical unit in the upper mediastinum that contains the esophagus,...

Shigeru Tsunoda, M. Sakaguchi, Shintaro Okumura et al. · 0 citations
Review Open access Aug 2026

P1.160. Role of Minimally Invasive Esophagectomy in Multidisciplinary Treatment for T4b Cervical Esophageal Cancer

Esophageal Cancer: Surgical Treatment of Esophageal Cancer No standard treatment exists for T4b (UICC 8th) cervical esophageal cancer. At our institution, definitive chemoradiotherapy (dCRT) (total dose > 50.4 Gy) is prioritized as initial therapy, and salvage surgery is performed only for persistent or re...

M. Sakaguchi, Shigeru Tsunoda, Shintaro Okumura et al. · 0 citations
Open access Jul 2026

Colorectal cancer co-opts an epidermal wound healing program during metastasis to generate disseminated tumor cells

It is shown that CRC cells transiently adopt a wound-healing program normally used by epidermal keratinocytes during tissue repair to enable metastatic dissemination, and this state is reversible, as cells reacquire primary tumor–like characteristics upon colonization of distant organs.

M. Sakahara, Takuya Okamoto, Kohei Kumegawa et al. · 0 citations

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