Author

K. Panageas

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Open access Sep 2026

Comprehensive analysis of germline pathogenic variants across melanoma

Although a heritable component is implicated in ~10% of melanomas, the prevalence and functional relevance of germline pathogenic variants (gPVs) in unselected patients remains unknown. We evaluated 701 patients with melanoma who underwent tumor-normal MSK-IMPACT sequencing (2015–2023) and germline analysis of ≥76 ca...

S. Lochrin, H. Walch, Y. Kemel et al. · npj Genomic Medicine · 0 citations

Aug 2026

Rule-Based Identification of a Reliable Real-World Cancer Recurrence Endpoint.

BACKGROUND Recurrence is a key oncologic endpoint but is difficult to automatically capture from electronic health records (EHR). METHODS We evaluated rule-based algorithms to detect recurrence and its timing using a publicly available clinico-genomic database of patients with breast, colorectal, non-small cell lung,...

J. Lavery, Samantha Brown, Chelsea Nichols et al. · Cancer Epidemiology, Biomark... · 0 citations