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Meta-analysis Open access Oct 2026

Gene-based association analysis of depression risk among European ancestry Parkinson’s disease patients

Depression is one of the most common and disabling non-motor symptoms in Parkinson’s disease (PD), yet its genetic basis remains poorly understood. Here, we investigate the genetic contributions to depression in PD by estimating the burden from common as well as low-frequency single nucleotide polymorphisms (SNPs) with...

Han-Wen Wang, K. Paul, Cynthia D. J. Kusters et al. · 0 citations
Open access Oct 2026

Longitudinal untargeted metabolomics of cognitive impairment in Parkinson's disease

Abstract INTRODUCTION Cognitive impairment is a common non‐motor symptom of Parkinson's disease (PD), yet the mechanism remains unclear. METHODS Longitudinal serum samples from PD patients in a community‐based case–control study were profiled, with cognition assessed by the Mini‐Mental State Examination at baseline and...

Yu-Yuan Lin, Yu Yu, Ke-Ren Zhang et al. · 0 citations

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