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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

K. Ratia

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2 papers indexed here

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Aug 2026

Dihydroorotate Dehydrogenase Inhibitors are Potent Antiviral Agents against Henipaviruses and Arenaviruses.

Hendra virus (HeV) and Nipah virus (NiV) are zoonotic henipaviruses associated with high mortality and are classified as Biosafety Level 4 (BSL-4) agents. To identify small molecule inhibitors, we performed a cell-based high-throughput screening (HTS) of an antiviral compound library using recombinant Cedar virus (rCed...

Yuanyuan Li, Jing Ma, Ryan Bott et al. · 0 citations
Aug 2026

Discovery of SARS-CoV-2 PLpro covalent inhibitors enabled by a novel reversible covalent chloroalkyne warhead.

These findings establish chloroalkyne as a promising target-directed reversible covalent warhead for PLpro inhibition and provide in vivo proof-of-concept for this chemistry in antiviral drug discovery, with potential for broader application to other cysteine proteases.

Divakar Indukuri, J. G. Achi, Boopathi Sownthirarajan et al. · 0 citations

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