Author

K. Riesbeck

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Open access Oct 2026

The CLEC7A Y238∗ variant and susceptibility to pneumonia: a prospective population-based cohort study and mechanistic investigation.

BACKGROUND DECTIN-1, a C-type lectin receptor encoded by CLEC7A, mediates antifungal immunity, but its antibacterial role remains unclear. We investigated, using human genetic and animal studies, whether the common loss-of-function CLEC7A Y238∗ variant (rs16910526) influences susceptibility to bacterial respiratory inf...

Oskar Thofte, Valdemar Öhnström, Linda Yamba Yamba et al. · EBioMedicine · 0 citations

Open access Sep 2026

Determinants associated with lower HPV vaccination uptake in the school-based program for girls - A follow-up of the Swedish National Immunization Program, 2013-2023.

BACKGROUND Human papillomavirus (HPV) vaccinations were introduced in the Swedish National Immunization Program (NIP) for girls in 2012. This study aims to examine socioeconomic factors among schoolgirls and their parents associated with low HPV vaccine uptake (first dose) according to the NIP schedule (aged 11-13 year...

Emma Appelqvist, E. Löf, S. Kühlmann-Berenzon et al. · Vaccine · 0 citations

Open access Aug 2026

Transcriptional Regulator FabR Is Associated with the Virulence of Non-typeable Haemophilus influenzae in Host-Pathogen Interactions.

Deletion of fabR reduced host cell adherence, increased serum sensitivity, enhanced IgG deposition, and decreased vitronectin binding compared with the wild-type strain, and ΔfabR mutants from multiple NTHi strains showed increased metabolic activity, indicating a conserved role for FabR in metabolic regulation.

Martina Janoušková, Yu-Ching Su, Sandra Jonsson et al. · Journal of Infectious Diseas... · 0 citations