Author

K. Sabapathy

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Open access Aug 2026

MucD regulates alginate biosynthesis through the proteolytic control of AlgX and AlgK in Pseudomonas aeruginosa

It is demonstrated that MucD represses alginate biosynthesis post-translationally, in addition to its previously implicated role in transcriptional regulation, which defines a distinct activation mechanism and regulatory function for MucD and provides new insight into bacterial HtrA-like serine proteases.

Yu-Jun Jiang, Xin-Fu Yan, R. Ero et al. · bioRxiv · 0 citations

Open access Jul 2026

Spermidine targets GGA-rich small RNAs for virulence regulation

Summary Spermidine (SPD), a polyamine essential for various biological processes, has long been recognized as a signaling molecule. Yet, its specific molecular targets and mechanisms of action remain elusive. In this study, we uncover a previously unknown mechanism whereby SPD selectively binds to small regulatory RNAs...

Chao Wang, Xiaoling Liu, Changqing Chang et al. · iScience · 0 citations