Open access
Oct 2026
Structural basis for Mg²⁺–glycine synergy in the tandem glycine riboswitch revealed by cryo-EM
Riboswitches are non-coding RNA sequences that control cellular processes through ligand binding. Conformational heterogeneity is fundamental to riboswitch functionality, yet this same attribute makes structural characterization of these mRNA elements challenging. Here, we use cryo-electron microscopy to characterize d...
N. Jespersen, J. D. Prajapati, Ankush Singhal et al.
· npj Structural Biology · 0 citations