Title: Genomic impact of the second plague pandemic on three human populations
Xiaodong Liu, K. Moore, S. Ebenesersdóttir et al.
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This study provides the most comprehensive assessment of IBS genetics to date, demonstrating reproducible polygenic inheritance and linking IBS risk to convergent neurogastrointestinal and novel cardiometabolic mechanisms, highlight specific biological pathways and actionable mechanisms and outline translational opportunities emerging from integrated computational analyses.