Tfh cell communication with myeloid compartments plays a key role in the inflammatory response in localized scleroderma: insights from skin scRNA sequencing.
Macrophages, T lymphocytes and NK cells are central to inflammatory responses in localized scleroderma (LS morphea), but their inflammatory signature and differentiation remain inadequately classified. This study examined the transcriptomes of these cell types to clarify their contribution to LS pathogenesis. Single-ce...