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K. Tsioufis

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Review Open access Oct 2026

Non-Invasive Assessment of Coronary Microvascular Dysfunction: From Flow Quantification to Clinical Decision Making

Coronary microvascular dysfunction (CMD) is a major mechanism of myocardial ischemia and adverse cardiovascular outcomes in patients with angina or dyspnea, both in the absence and in the presence of obstructive coronary artery disease. Because the coronary microcirculation cannot be visualized directly with routine an...

Panagiotis Theofilis, A. Sakalidis, Kyriakos Dimitriadis et al. · 0 citations
Review Oct 2026

Post-treatment risks of transcatheter aortic valve implantation: should we be increasing preventative measures?

INTRODUCTION Transcatheter aortic valve implantation (TAVI) has become an established treatment for severe aortic stenosis across an expanding risk spectrum. As indications extend to younger and lower-risk patients, post-treatment complications with implications for survival, quality of life, and valve durability requi...

Panagiotis Theofilis, P. Vlachakis, George Koutsopoulos et al. · 0 citations
Open access Oct 2026

Beta-blockers after acute coronary syndrome: insights across the ejection fraction spectrum

To evaluate the association between beta-blocker (BB) prescription and long-term all-cause mortality after acute coronary syndrome (ACS), and to assess whether this varies across the left ventricular ejection fraction (LVEF) spectrum. We analysed ACS patients from the retrospective multicentre CardioMining...

E. Tsiartas, Sokratis Oikonomou, A. Iordanidou et al. · 0 citations
Review Sep 2026

Complications After Permanent Pacemaker Implantation in Patients with Congenital Complete Atrioventricular Block: A Systematic Review and Meta-analysis.

BACKGROUND Congenital complete atrioventricular block (CCAVB) requires pacing from early life, yet the long-term burden of pacing-induced cardiomyopathy (PICM), mortality, and device-related complications has not been quantitatively synthesized. OBJECTIVE To determine the incidence of PICM, mortality, and device-rela...

P. Vlachakis, Panagiotis Theofilis, Maria Drakopoulou et al. · 0 citations
Open access Oct 2026

Association Between Diet Quality and 20-Year Heart Failure Incidence: Findings from the ATTICA Cohort Study (2002–2022)

Background/Objectives: Diet quality is a potentially modifiable determinant of heart failure (HF), yet evidence regarding its long-term association with HF incidence remains limited. This study examined the association between baseline diet quality and 20-year incident HF in the population-based ATTICA cohort. Methods:...

C. Chrysohoou, P. Iliakis, I. Daha et al. · 0 citations
Review Aug 2026

Transcatheter Atrial Shunting in Patients With Heart Failure: A Systematic Review and Meta-Analysis.

Despite improvements in heart failure (HF) management, there is still a significant residual risk for adverse events in both trial and real-world settings. Transcatheter atrial shunting is a novel intervention aiming to restore normal hemodynamics and thus improve outcomes. The aim of this systematic review and meta-an...

N. Pyrpyris, Kyriakos Dimitriadis, Eirini Beneki et al. · 0 citations
Review Open access Aug 2026

Redo-Transcatheter Aortic Valve Implantation Versus Surgical Explantation in Patients With Previous Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis.

BACKGROUND As transcatheter aortic valve implantation (TAVI) expands to younger and lower-risk populations, failed transcatheter heart valves are increasingly encountered, yet the optimal reintervention strategy remains uncertain. This meta-analysis aimed to compare the outcomes of redo-TAVI (TAVI-in-TAVI) versus surgi...

N. Ktenopoulos, A. Apostolos, D. Terentes-Printzios et al. · 1 citation
Sep 2026

Prognostic significance of cardiopulmonary exercise testing parameters for predicting all-cause mortality in patients with heart failure: a cohort study.

BACKGROUND Heart failure (HF) remains a significant challenge in global healthcare, contributing to frequent hospitalizations and elevated mortality rates. Cardiopulmonary exercise testing (CPET) provides a non-invasive method of assessing how the cardiovascular, respiratory, and musculoskeletal systems function. OBJ...

Christina Chrysohoou, M. Dulay, C. Fragoulis et al. · 0 citations
Review Sep 2026

New pharmacologic and interventional horizons in hypertension and nondialysis chronic kidney disease: bridging innovation and clinical translation.

A comprehensive overview of emerging pharmacologic and interventional approaches for BP management in nondialysis CKD is provided, highlighting mechanism-driven innovations and their potential clinical translation.

A. Damianaki, P. Iliakis, A. Vakka et al. · 0 citations
Review Open access Jul 2026

Multimodality echocardiography in structural heart disease: the evolving role of the interventional imager

This review outlines the expanding role of echocardiography across the spectrum of TSHIs, highlighting the importance of multimodality imaging, including three-dimensional transoesophageal echocardiography (3D TEE), intracardiac echocardiography (ICE) and fusion imaging techniques, for comprehensive structural evaluati...

N. Ktenopoulos, K. Vlasopoulou, P. Vlachakis et al. · 0 citations
Review Open access Aug 2026

Prophylactic implantation of implantable cardioverter-defibrillator for the primary prevention of sudden cardiac death after myocardial infarction: protocol for systematic review and meta-analysis of randomised controlled trials

A systematic review and meta-analysis will evaluate and provide primary evidence for the effectiveness of prophylactic implantation of TV-ICDs on all-cause mortality in patients who experienced MI, aiming for primary prevention of SCD after MI.

A. Amarasekera, Anoja W. Gunaratne, J. Kovoor et al. · 0 citations

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