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Author

K. Yamaguchi

2 papers indexed here

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Open access Aug 2026

Epigenetic markers expand genetic risk estimation in acute myeloid leukemia.

Gene mutations and chromosome abnormalities are important components of prognostication in acute myeloid leukemia (AML). Here we assessed whether DNA methylation patterns in AML patients can augment risk assessments provided by genetic and other markers to better predict outcomes. Unsupervised DNA methylation patterns...

Salma B. Abdelbaky, B. Giacopelli, J. Kohlschmidt et al. · 0 citations
Open access Sep 2026

IL-15 signaling during a critical NK cell developmental window subverts maturation and KIR acquisition.

Natural killer (NK) cells are key mediators of immune surveillance following hematopoietic stem cell transplantation (HSCT). However, despite the post-conditioning spike in interleukin-15 (IL-15), NK cell maturation is frequently delayed following HSCT. Here, we show that during in vitro NK cell development from CD34+...

Michael A. Ruesch, Noah T. Koenigs, E. Troy et al. · 0 citations

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