Author

K. Zengler

2 papers indexed here

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Open access Oct 2026

Targeting catecholate siderophore systems enables precision depletion of gut enterobacteria during colitis

Adherent-invasive Escherichia coli (AIEC) is frequently isolated from the dysbiotic gut microbiome in inflammatory bowel disease and is implicated in disease progression, highlighting its potential as a therapeutic target. Here we show that iron acquisition is essential for AIEC colonization of the inflamed gut. Mechan...

Grant J. Norton, Anna M. Dudek, R. Gerner et al. · bioRxiv · 0 citations

Open access Sep 2026

Synthesis-driven reverse metabolomics reveals 3-hydroxy N-acyl amides as gut microbial molecules

ABSTRACT 3-Hydroxy N-acyl amides are bioactive lipids with reported anti-obesity and glucose-regulating effects, yet they are rarely detected in untargeted metabolomics studies because they are largely absent from existing spectral reference libraries. To address this gap, we synthesized an MS/MS spectral resource comp...

Victoria Deleray, Vincent Charron-Lamoureux, Kyle Vittali et al. · mSystems · 0 citations