K. Zientek

PROTEOMIC IDENTIFICATION OF NOVEL AUTOANTIBODY TARGETS IN RHEUMATOID ARTHRITIS AND DIAGNOSTIC PERFORMANCE OF TGF-BETA-1-INDUCED PROTEIN AND SERUM AMYLOID A AUTOANTIBODIES

GNL3 SUMOylation is essential for DNA double-strand break repair by homologous recombination

DNA double-strand break repair via homologous recombination is critical for maintaining genomic integrity and requires proper DNA end resection. Here, we identify GNL3, a nucleolar GTP-binding protein, as a key regulator of homologous recombination in human cells via SUMOylation-dependent control of DNA end resection....