Author

Kai-Guang Zhang

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Open access Sep 2026

WDR12 Promotes Glucose Metabolism via PFKFB4 Upregulation in Gastric Cancer

ABSTRACT Metabolic reprogramming is a hallmark of gastric cancer (GC); however, the role of transcriptional regulators in modulating glycolysis remains incompletely understood. By integrating proteomic, transcriptomic, and CRISPR‐based functional screening datasets, we identified WDR12, a WD40‐family protein that is up...

Ru-Tong Zhang, De-Hua Liu, Xiao-Xi Feng et al. · Cancer Science · 0 citations

Open access Sep 2026

Mitotic assembly of respiratory supercomplexes ensures accurate cell division and fuels tumor growth.

As cells progress from interphase into mitosis, fluctuating metabolic demands coincide with mitochondrial fission. However, the mechanisms by which mitochondria coordinate morphological changes and metabolic adjustments during mitosis remain poorly understood. Using proteomic analysis of BN-PAGE fractions, we show that...

Ting Wang, Ao-Xing Cheng, Ling-Yu Kong et al. · EMBO Reports · 0 citations