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Author

Kaili Fan

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Open access Sep 2026

A single-nucleus multi-omic atlas of gene regulation across 21 adult human tissues

Diverse human cell types establish specialized functions through lineage- and context-specific regulatory programs. Interpreting non-coding genetic risk requires integrated multi-omic reference maps that directly connect regulatory DNA to cellular expression across human tissues. Here we present a single-nucleus multi-...

Kai-Li Fan, Amrita Sule, A. Guillaumet-Adkins et al. · 0 citations
Open access Jul 2026

An encyclopedia of human enhancer–gene regulatory interactions

An encyclopedia of enhancer–gene regulatory interactions in the human genome is built, revealing global properties of enhancer networks, identifying differences in regulatory complexity across genes, and improving analyses linking noncoding variants to target genes and cell types for common, complex diseases.

A. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh et al. · 6 citations

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