Thermosensitive RGD-modified liposomes co-loading Fe3O4 and sorafenib for synergistic photothermal-chemotherapy of hepatocellular carcinoma.
Sorafenib (SRF) therapy for hepatocellular carcinoma (HCC) is limited by dose-limiting toxicities, inadequate tumor exposure, and the inability to confine drug action spatiotemporally, leading to suboptimal efficacy and a narrow therapeutic window. Here we report an RGD-functionalized DPPC-based thermosensitive liposom...