Kai-Ting Zhang

To establish an indirect ELISA method for the detection of human brucellosis based on signal peptide-truncated recombinant Cu/Zn SOD and its preliminary clinical verification

Background Serological diagnosis of brucellosis is hindered by cross-reactivity with lipopolysaccharide (LPS) antigens, resulting in insufficient specificity and sensitivity, which remains one of the major bottlenecks in current clinical testing for brucellosis. Methods To overcome this limitation, we developed an indi...