The multifaceted role of E3 ubiquitin ligase SMURF1 in cellular signaling and disease regulation
SMAD-specific E3 ubiquitin ligase 1 (SMURF1) is a key regulator of cellular processes through its role in ubiquitination and degradation of various substrate proteins. As a member of the NEDD4 family of E3 ubiquitin ligases, SMURF1 is involved in modulating critical signaling pathways which regulate cellular function...