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Review Open access Aug 2026

The multifaceted role of E3 ubiquitin ligase SMURF1 in cellular signaling and disease regulation

SMAD-specific E3 ubiquitin ligase 1 (SMURF1) is a key regulator of cellular processes through its role in ubiquitination and degradation of various substrate proteins. As a member of the NEDD4 family of E3 ubiquitin ligases, SMURF1 is involved in modulating critical signaling pathways which regulate cellular function...

Xin-Lei Wu, Kai Yang · 0 citations

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