AmbiModBench: Benchmarking Gene Perturbation Prediction Beyond Shared Responses
Predicting cellular responses to genetic perturbations helps prioritize experiments in single-cell genomics, where exhaustive measurement is infeasible. While computational models increasingly predict these responses, three evaluation deficiencies obscure what their scores demonstrate. First, absolute metrics cannot se...
Si-Kai Huang, Zhi-Wen Yang, Kai Yu et al.
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