Sep 2026
CCND1 Mitigates Ischemia-Induced Pathological Cardiac Remodeling by Promoting Cardiac Monocyte-Derived Macrophage Transition to a Reparative Phenotype.
BACKGROUND The innate immune system plays a pivotal role in orchestrating the response to myocardial infarction (MI), with monocytes and macrophages acting as central mediators of tissue injury and repair. Following MI, a dynamic sequence of inflammatory, anti-inflammatory, and reparative phases unfolds over the course...
Chu-Han Wang, Hui-An Han, Kai-Lai Li et al.
· Circulation · 0 citations