Open access
Aug 2026
XRCC1 Enables the Efficient Local Search for DNA Damage by DNA Polymerase Beta
It is demonstrated that XRCC1 reshapes pol β search behavior to promote efficient local damage recognition, providing a mechanistic basis for how BER factors coordinate lesion detection and processing to maintain genomic stability.
Spencer H. Thompson, Kaitlin M. DeHart, M. Schaich et al.
· bioRxiv · 0 citations