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Author

Kaiyun Zheng

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Open access Aug 2026

CRISPR/Cas9-mediated generation of a homozygous MT4 knockout mouse embryonic stem cell line.

The CRISPR/Cas9 system is utilized to generate a homozygous Mt4 knockout (Mt4-/-) mouse embryonic stem cell (mESC) line that maintains normal morphology, pluripotency, and the ability to differentiate into all three germ layers.

Huan-Xin Zhou, Yine Li, Meiyan Jia et al. · 0 citations