AI-based characterization of Alzheimer's disease phenotypes from population-scale single-cell data.
The complexity of Alzheimer's disease (AD) manifests in diverse clinical phenotypes, including cognitive impairment and neuropsychiatric symptoms. However, the etiology of these phenotypes remains elusive. To address this, the PsychAD project generated a population-level single-nucleus RNA sequencing dataset comprising...
Chen-Feng He, Athan Z. Li, Kalpana Hanthanan Arachchilage et al.
· Nature Medicine · 1 citation