Multi-omic analysis identifies mitochondrial dysfunction as a key feature of hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is an inherited cardiovascular disorder marked by left ventricular hypertrophy, known to be caused by genetic mutations in sarcomere proteins, such as MYH7 and MYBPC3. Despite advancements in our understanding of HCM genetics, the relationship between genetic variants and clinical outc...