Author

Kamal Shah

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Review Oct 2026

A Comprehensive Review of Triple-Negative Breast Cancer and Recent Advances in Acridone Derivatives for Its Treatment

Triple-Negative Breast Cancer (TNBC) is an aggressive breast cancer, poorly responsive to drugs targeting hormone receptors in other breast cancer types. It is molecularly complex and aggressive, hindering therapy. Molecular characterization of TNBC has identified mutations and key signaling pathways in its develop...

Abhishek Kumar, Kamal Shah · Current Topics in Chemistry · 0 citations

Review Sep 2026

A Comprehensive Overview of Pyridine and Pyrimidine Derivatives for Anticancer Drug Development.

INTRODUCTION Pyridine and pyrimidine-based compounds are known to be a part of the structure of DNA and RNA; however, it has been found that these compounds have been incredibly useful in the development of anticancer drugs. The pharmacokinetics of the compounds, along with their potential to target key oncoproteins su...

Aakash Sharma, J. Sahu, Kamal Shah et al. · Current Organic Synthesis · 0 citations

Review Aug 2026

Targeting the Hallmarks of Ageing: Pharmacological Challenges and Breakthroughs in CRISPR Delivery Systems and Future Prospects.

CRISPR has emerged as a next-generation gene-editing tool with the potential to target the molecular pathways associated with ageing and related disorders. It functions through RNA-guided Cas nucleases, directing DNA cleavage and utilizing the native DNA repair machinery for genetic manipulations. Advances in CRISPR te...

Sakshi Rathore, Akash Gupta, Kamal Shah et al. · Ageing Research Reviews · 0 citations