Review
Open access
Sep 2026
Macrophage states and immunometabolic adaptation in peritoneal metastases from colorectal cancer
Immunotherapy responses in colorectal cancer peritoneal metastases (CRCPM) are not determined by mismatch repair (MMR) status alone. Most MMR-proficient/microsatellite-stable (pMMR/MSS) tumors have low baseline sensitivity, while MMR-deficient/microsatellite instability-high (dMMR/MSI-H) tumors do not respond uniformly...
Wei-Hao Chen, Jia-Li Wei, Yi Wang et al.
· Frontiers in Immunology · 0 citations