Author

Karen Palacio-Rodríguez

2 papers indexed here

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Open access Sep 2026

Structural mechanism of nuclear membrane sealing by LEM2-ESCRT-III

In open mitosis, re-establishing nucleocytoplasmic compartmentalization requires the LEM2-ESCRT machinery to coordinate spindle clearance with sealing of the remaining nuclear envelope pores. The structural basis of this topologically unique and fundamental membrane-remodeling process is poorly understood. Here, we com...

Mareike A. Jordan, Karen Palacio-Rodríguez, Ramesh Adakkattil et al. · bioRxiv · 0 citations

Open access Jul 2026

Identification of lipid specificity in membrane organizing protein complexes

Using super-resolution microscopy and molecular dynamics simulations, it is demonstrated that phosphatidylethanolamine stabilizes both NDC1 and MIC60 in highly curved membrane nanodomains, indicating that major membrane organizing complexes are positioned by selective lipid-protein interactions.

Katelyn C. Cook, Karen Palacio-Rodríguez, Kristi Bohlig et al. · bioRxiv · 1 citation