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Author

Karim Al Hasanieh

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Review Open access Oct 2026

Durability of Implanted Cervical Vagus Nerve Stimulation in Treatment-resistant Major Depression: Summary of Findings and Potential Mechanisms of Action

Treatment-resistant depression (TRD), major depressive disorder (MDD) characterized by inadequate response to a series of antidepressant treatments, is a major clinical challenge. Implanted vagus nerve stimulation (VNS), surgical placement of a pulse generator with an electrical lead attached to the cervical vagus nerv...

Karim Al Hasanieh, C. Zorumski, H. Sackeim et al. · 0 citations

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