Author

Karim Matmat

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Open access Oct 2026

RNA modular expression laboratory (RNAmel): an integrated R/Shiny platform for reproducible bulk RNA-seq analysis and interpretation

Bulk RNA-sequencing is routine, but turning a gene-level count matrix into biological insight still requires combining specialised tools for quality control, differential expression, dimensionality reduction, enrichment, co-expression networks, and activity inference. These steps are typically performed either wi...

Karim Matmat, Tamara Pfanner, Rafael P. Silveira et al. · BMC Bioinformatics · 0 citations

Open access Aug 2026

Integrative Transcriptomic Analysis Reveals Impaired Oligodendrocyte Maturation and Myelination Signature in the Hippocampus of a Murine Model of Neuropsychiatric Lupus

These findings challenge an inflammation-centric interpretation of NPSLE hippocampal pathology, highlighting instead an additional contribution of impaired oligodendrocyte maturation.

Karim Matmat, Noémie Karabacz, Céline Keime et al. · International Journal of Mol... · 0 citations