Low-grade systemic inflammation increases with age and accompanies many age-associated lifestyle-related diseases, yet substantial inter-individual variability exists beyond chronological age. Given the gut microbiota’s role in immune regulation, we analyzed paired fecal microbiota profiles, 30 plasma cytokines, and 19...
C. Eriksen, Ioanna Chatzigiannidou, R. I. Dehli et al.· Nature Communications· 0 citations
A genome-resolved metagenomic analysis of 455 soil samples collected at different depths and seasonal stages across two Danish agricultural fields representing sandy and clay soil types revealed extensive biosynthetic and metabolic potential, including 46,913 biosynthetic gene clusters and prevalent genes linked to nit...
Ioanna Chatzigiannidou, Tanvi Taparia, P. L. Johansen et al.· ISME Communications· 0 citations
This work leverage 1,150 complete genomes to construct genome-scale metabolic models, demonstrating that draft assemblies introduce systematic artifacts and omit critical transport functions, and connects genome completeness with microbial ecological organization and provides a framework for linking metabolic interacti...
Yu-He Gu, Haoyu Wang, Jin-Long Yang et al.· Cell Reports· 0 citations
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