Kasper Engholm-Keller

Phosphorylation of α-synuclein directs trafficking of the v-SNARE synaptobrevin-2.

α-Synuclein has been extensively studied for its role in Parkinson's disease, however its native function remains unclear. Several lines of evidence suggest it modulates presynaptic function. As many presynaptic proteins have their functions regulated by phosphorylation, we sought to determine whether α-synuclein, a kn...