Abstract B009: DNA-proximal MYB phosphorylation is required for oncogenic transcription in acute myeloid leukemia
Dysregulation of gene expression is an essential feature of most human cancers, including acute myeloid leukemia (AML), yet genetically distinct AML subtypes often share pathologic dependencies on transcription factors and gene-regulatory mechanisms. In particular, MYB is aberrantly activated in most studied forms of...