Author

Kateepe Asn Shanaka

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Open access Aug 2026

NAT10 is critical to block RNA sensing-induced IFN-β transactivation in viral infection

ABSTRACT Cells detect invading viruses and produce type I interferons (IFNs) to stimulate an innate antiviral effector response. However, IFN levels must be fine-tuned to achieve antiviral efficacy while limiting hyperinflammatory and tissue-damaging effects. Here, we report that NAT10, a histone and cytidine acetyltra...

Youngmin Park, Yan Liu, Jinshan He et al. · mBio · 0 citations

Open access Jul 2026

Levosimendan inhibits HIV-1 infection in myeloid cells via counteracting RIOK1.

LSM is a promising LPA to inhibit HIV-1 infection in myeloid cells via counteracting RIOK1 and it is demonstrated that overexpression of a predicted drug target of LSM, the conserved serine/threonine kinase RIOK1 (RIO kinase 1), overcomes LSM's anti-HIV effect.

Jinshan He, Jie Ma, Youngmin Park et al. · Antiviral Research · 0 citations