Katherine E. Gandy

Mesenchymal Stem Cells as a Therapeutic Treatment for Osteogenesis Imperfecta: Current Understanding Through Clinical Trials

Osteogenesis Imperfecta (OI), also known as brittle bone disease, is a rare heterogeneous disorder with an incidence of 1 in 15,000 to 20,000 live births. Currently, OI has been associated with 19 different gene mutations, primarily affecting genes responsible for collagen type I production and resulting in clinical ma...