Open access
Jul 2026
Treatment Responses Alter Myeloid Activation in BRAF-Mutant Melanoma 2252856
This work establishes for the first time that BRAFi promotes myeloid-mediated induction of T cell activation, which is lost at resistance but can be rescued with the addition of CDDO- me, and provides the foundation for its potential use in combination therapies for melanoma.
Chen-Yu Wang, G. Torres, Helen C. Jarnagin et al.
· Journal of Immunology · 0 citations