Author

Katsuhiro Ito

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Open access Sep 2026

50 Tumor–Myeloid Multicellular Programs Reveal ECM-Associated Macrophage Polarization in ccRCC

Abstract Background Clear cell renal cell carcinoma (ccRCC) is characterized by a highly heterogeneous tumor immune microenvironment. However, how tumor-intrinsic programs shape immune cell states remains incompletely understood. We aimed to identify multicellular programs (MCPs) linking tumor and immune compartments a...

Katsuhiro Ito, S. Kashima, Rishabh Rout et al. · The Oncologist · 0 citations