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Author

Kaui P. Lebarbenchon

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2 papers indexed here

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Open access Aug 2026

Early cardiac proteomic profiling in a long-latency doxorubicin cardiomyopathy model exhibits sexual dimorphism for cardioprotection

Anthracycline-induced cardiotoxicity remains a major limitation in cancer therapy, with substantial inter-individual variability in susceptibility, including documented sex differences. However, the molecular basis underlying these disparities remains incompletely understood. In this study, we employed large-scale data...

Sogol Sedighi, Li-Jun Chen, Yue-Fen Wang et al. · 0 citations
Open access Sep 2026

Structural variation in repeat elements is widespread in normal human tissues and in tumorigenesis

Somatic mosaicism contributes to genomic variation, yet postzygotic structural variants remain under-characterized. We performed long- and short-read WGS from multiple individuals (n=47 normal tissues; n=168 samples) and identified mosaic structural variants in all individuals and germ layers, impacting a median 285.2...

A. Annapragada, James R. White, Hope Orjuela et al. · 0 citations

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