Author

Kaya Epstein

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Open access Aug 2026

A synthetic NKG2A engager enables long-term persistence of HLA-deficient allogeneic engineered Tregs.

An improved NKG2A engager is reported to selectively inhibit NKG2A⁺ NK cells while avoiding activation of NKG2C⁺ subsets, thereby overcoming a key limitation of the natural ligand HLA-E.

Tingxi Guo, Kaya Epstein, M. Hoover et al. · EMBO Molecular Medicine · 0 citations

Open access Jul 2026

HLA-Shuttle: A system for enhancing antigen presentation in immunologically cold tumors 2258016

HLA-Shuttle restores antigen presentation in immunologically cold tumor cells, facilitating identification of TAAs with favorable therapeutic potential and identifying multiple novel tumor associated antigens (TAAs) from both known and novel cancer immunotherapy targets.

Daniel Hwang, Molly C. Erdman, Santosh Adhikari et al. · Journal of Immunology · 0 citations