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Kayo Yukawa

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Open access Oct 2026

Suppression of Tau-tubulin kinase 1 mitigates tau phosphorylation, and Aβ mediated neurotoxicity via altered kinase network.

Tau-tubulin kinase-1 (TTBK1) is a neuron-specific serine/threonine tau kinase that is highly expressed in the entorhinal and hippocampal regions and phosphorylates microtubule-associated protein tau at sites relevant to Alzheimer's disease (AD), thereby contributing to early tau pathology. Targeting TTBK1 can be a prom...

Kayo Yukawa, Satoshi Muraoka, Samtani Grace et al. · 0 citations

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