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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Kazuhiko Nakabayashi

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2 papers indexed here

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Sep 2026

Postzygotic NRAS Variants and Subsequent Copy-Neutral Loss of Heterozygosity Underlie Speckled-Pattern Formation in Nevus Spilus-Type Congenital Melanocytic Nevus.

Nevus spilus-type congenital melanocytic nevus (NS-CMN) is characterized by a background brown macule with superimposed black macules or plaques; however, the mechanism underlying speckled-pattern formation in human skin remains unclear. We performed clinicopathological and molecular analyses of three NS-CMN cases usin...

Kana Ueda, A. Yoshioka, Harumi Fujita et al. · 0 citations
Open access Sep 2026

Genomic imprinting of the metabolic regulator gene Klf14 is regulated by a paternal sub-TAD anchored at Mest.

KLF14 acts as a master regulator of gene expression in adipose tissue and variants at the human KLF14 gene show reproducible association with type 2 diabetes and metabolic syndrome. Risk alleles are only pathological when maternally inherited, consistent with the observation that KLF14/Klf14 is a maternally expressed i...

Amanda Ha, Natsuki Hayashi, Aaron B. Bogutz et al. · 0 citations

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