Open access
Sep 2026
An ALKBH3 Inhibitor HUHS199 Suppresses Proliferation of Glioblastoma Cells by Targeting 1‐Methyladenosine on GADD45A mRNA
Findings suggest that ALKBH3 promotes GBM cell proliferation via m1A demethylation of GADD45A mRNA, and presents HUHS199 as a first‐in‐class candidate for GBM treatment.
Manami Yamada, H. Hase, Honoka Kitamura et al.
· Chemical Biology and Drug De... · 0 citations