Author

Ke He

2 papers indexed here

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Open access Oct 2026

Baihe Zhimu Decoction ameliorates anxious depression via PI3K/AKT/mTOR pathway‐mediated neuroprotection and inhibition of hippocampal neuronal apoptosis

Abstract Background Anxious depression involves severe emotional dysregulation with a high risk of relapse and suicide. Although the classical Traditional Chinese Medicine formula Baihe Zhimu Decoction (BZD) is widely used for affective disorders, its underlying mechanisms remain poorly understood. Methods In this stud...

Yuan-Shan Han, Ke He, Hao-Lan Yang et al. · Animal Models and Experiment... · 0 citations

Review Open access Sep 2026

Natural products as selective estrogen receptor modulators in depression-related disorders: Balancing antidepressant efficacy and safety.

Depression-related disorders remain major clinical challenges, and increasing evidence suggests that estrogen receptor (ER) signaling is involved in processes relevant to depression, including neuroinflammation, synaptic plasticity, neurotransmission, and stress regulation. Natural products and Traditional Chinese Medi...

Rong Chen, Jie Luo, Ke He et al. · Biomedicine & pharmacotherap... · 0 citations